10 eczema facts

In this article we will describe 10 facts about eczema.

Key Points

  • Eczema is a chronic inflammatory skin condition characterized by dry, itchy, and scaly skin.
  • Prevalence in the UK is approximately 15-20% in children and 5-10% in adults.
  • Atopic eczema is the most common type, often associated with asthma and allergies.
  • Diagnosis is primarily clinical, with investigations reserved for uncertain cases or severe disease.
  • Treatment focuses on topical corticosteroids, moisturizers, and lifestyle modifications.

1. Definition

  • Eczema, also known as atopic dermatitis, is a chronic or recurrent inflammatory skin condition marked by dryness, itching, and scaling.
  • The term ‘eczema’ encompasses various clinical entities, including atopic, contact, seborrhoeic, and nummular eczema.
Types
  • Atopic Eczema: Most common type, often associated with asthma, allergies, and family history.
  • Contact Dermatitis: Caused by skin contact with irritants or allergens.
  • Seborrhoeic Eczema: Typically affects oily areas, such as scalp, face, and chest.
  • Nummular Eczema: Coin-shaped patches, often on legs.
  • Dyshidrotic Eczema: Vesicular lesions on palms and soles.

2. Epidemiology

  • Prevalence in UK children: 15-20%.
  • Prevalence in UK adults: 5-10%.
  • Higher incidence in urban areas and developed countries.
  • Increased prevalence in families with atopic diseases.

3. Risk Factors

  • Family history of eczema, asthma, or allergies.
  • Urban residence.
  • Developed country.
  • Hygiene hypothesis (reduced exposure to childhood infections).
  • Genetic predisposition.

4. Causes

  • Genetic factors.
  • Environmental triggers (allergens, irritants, stress).
  • Imbalanced immune response.
  • Skin barrier dysfunction.

5. Symptoms

  • Dry, scaly, or cracked skin – especially on flexor surfaces (front of elbow, back of knee).
  • Intense itching (pruritus).
  • Redness and inflammation.
  • Skin thickening (lichenification).
  • Papules, vesicles, or pustules.

Typical flexural (i.e. in the creases) eczema

6. Diagnosis

Primarily clinical, based on:
  • History.
  • Physical examination.
  • Symptom severity.
Investigation

Reserved for:
  • Uncertain diagnosis.
  • Severe disease.
  • Suspected allergies or infections.
Investigations may include:
  • Skin prick testing.
  • Patch testing.
  • Blood tests (IgE, eosinophils).
  • Skin scraping or biopsy.
Differential Diagnosis
  • Psoriasis.
  • Dermatitis herpetiformis.
  • Ichthyosis.
  • Allergic contact dermatitis.
  • Scabies.

7. Treatment

  • Topical Corticosteroids: First-line treatment for inflammation.
  • Moisturisers: Emollients and humectants for dry skin.
  • Topical Immunomodulators: For severe or recalcitrant cases.
  • Antibiotics: For secondary infections.
  • Lifestyle Modifications:
    • Avoid soaps and harsh cleansers.
    • Wear breathable clothing.
    • Maintain skin hydration.
    • Control anxiety.
When to see a doctor with eczema 
  • Initial diagnosis.
  • Severe or worsening symptoms.
  • Poor response to treatment.
  • Suspected complications (e.g. skin infections).
  • Consider referral to dermatology for severe or complex cases.

8. Complications

  • Secondary skin infections (bacterial, viral, or fungal).
  • Eczema herpeticum (widespread viral infection)
  • Lichenification and skin thickening.
  • Mental health impacts (anxiety, depression).

9. Prognosis

  • Variable disease course.
  • Remissions and exacerbations common.
  • Early intervention and adherence to treatment improve outcomes.

10. Prevention

  • Breastfeeding and maternal avoidance of allergenic foods.
  • Early introduction of solids.
  • Avoidance of soaps and harsh cleansers.
  • Regular moisturising.
  • Stress management.

Summary

We have described 10 facts about eczema. We hope it has been helpful.