10 key facts about COVID-19

In this article we will describe 10 key facts about COVID-19.

1. Definition and Cause

COVID-19, caused by the SARS-CoV-2 coronavirus, is an infectious respiratory illness first identified in Wuhan, China, in December 2019.

2. Transmission

COVID-19 spreads via:
  • Respiratory droplets (coughing, sneezing, talking)
  • Close contact
  • Contaminated surfaces and objects.

3. Symptoms

Common symptoms include:
  • Fever
  • Cough
  • Fatigue
  • Shortness of breath
  • Loss of taste/smell
  • Muscle pains
  • Diarrhoea.
Note: Approximately 80% of symptomatic cases are mild, 15% moderate, and 5% severe.

4. Incubation and Duration

  • Incubation: Symptoms typically appear within 5-6 days (range 2-14) post-exposure
  • Duration:
    • Mild cases: 1-2 weeks
    • Severe cases: Up to 6 weeks or longer
    • Long COVID: Symptoms persisting over 3 months
5. At-risk Groups
At-risk groups include:
  • Older adults (65+)
  • Young children
  • Underlying health conditions (diabetes, heart disease)
  • Immunocompromised individuals.

6. Treatment

Most patients require no treatment. For those requiring treatment:
  • Medication:
    • Antivirals (Remdesivir, Lopinavir/Ritonavir, Oseltamivir, Molnupiravir, Paxlovid)
    • Anti-inflammatory drugs (Dexamethasone, Prednisolone, Tocilizumab)
    • Immunomodulators (Baricitinib, Tofacitinib)
  • Oxygen therapy
  • Hospitalisation +/- ICU/ventilation (severe cases)
7. Prevention
Recommended measures:
  • Vaccination
  • Mask-wearing
  • Social distancing
  • Hand hygiene
  • Avoiding crowded areas.
8. Vaccine Efficacy

COVID-19 vaccines significantly reduce severe illness, hospitalization, and mortality.

9. Mortality and Complications

  • Mortality rate: Approximately 1%, varying by vaccination status, age, variant, and underlying health conditions
  • Increased mortality: 5% (75+ years), 15% (85+ years)
  • Long COVID: Affects approximately 2% of the UK population, with 70% experiencing symptoms beyond 1 year.

10. Global Impact

As of 24 December 2024:
  • 776 million reported cases
  • 7 million reported deaths
  • Widespread economic disruption.

Summary

We have described 10 key facts about COVID-19. We hope it has been helpful.