- Infections, including sepsis, or most bacterial, viral, and fungal infections
- Autoimmune diseases like rheumatoid arthritis (RA), lupus (SLE) and ulcerative colitis (UC)
- Cancer
- Cardiovascular disease, like a myocardial infarction (heart attack)
- Major trauma.
How quickly does CRP go up and go down again?
This is summarised in this diagram. It comes down if the cause is getting better.
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Note. It starts rising at 4-6 hours.