Anaphylaxis – medical revision notes

What?

A life threatening allergic reaction. It has a rapid onset, with rapid progression of symptoms.

Signs

  • Flushing
  • Angioedema
  • Urticaria
  • Shortness of breath
  • Wheeze
  • Chest tightness
  • Respiratory arrest
  • Tachycardia
  • Bradycardia.

Triggers

  • Food products such as peanuts and milk
  • Medications such as antibiotics
  • Insect stings
  • Latex
  • Exercise.

Risk Factors

  • Allergies
  • Asthma
  • Atopic dermatitis
  • CVD
  • Previous anaphylactic reactions.

Top Tip. ‘Triple A’ = Allergies, Asthma, Atopic dermatitis

Treatment

In adults and children over the age of 12 years.

  1. Adrenaline given intramuscularly – Dosage = 0.5ml of 1 in 1000 (500mcg)
  2. After 5 minutes if there is no change/response to medication administer another dose of IM adrenaline.
  3. Adrenaline injections should be given in to the thighs of the patient.

Why is adrenaline useful in an anaphylactic reaction?

  • Prevents and relieves airway obstruction from mucosal oedema
  • Powerful inotropic and chronotropic effects relieve hypotension and shock
  • Relieves bronchoconstriction.