What is a high blood creatinine level?

  • Blood creatinine > 120 mcmol/L is above normal and a concern – and may indicate chronic kidney disease (CKD)
  • Blood creatinine > 150 mcmol/L is raised and usually problem – i.e. CKD (or AKI)
  • Blood creatinine > 200 mcmol/L is high and always a problem – it indicates Stage 4 CKD or worse
  • Blood creatinine >300 mcmol is a major concern – and requires prompt action
  • Blood creatinine >500 mcmol/L is life-threatening kidney failure – and dialysis is (usually) required.

What is creatinine – and what is it used for?

It is a blood test/number that reflects kidney function; the lower the creatinine GFR, the better the kidney function, the better.

The creatinine is used to:

  • Diagnose CKD (and AKI)
  • Monitor – changes in kidney function over time 
  • Decide – whether you need dialysis or a kidney transplant.

What is a normal creatinine level?

A normal creatinine level is 60-120 mcmol/L (in adults).

How does creatinine relate to GFR?

The GFR is derived from the creatinine (by the computer putting it into a mathematical equation) – but, unlike creatinine, for GFR the higher the number, the better is the kidney function.

CKD STAGE; GFR = GLOMERULAR FILTRATION RATE.   CKD/GFR classification

Blood creatinine levels at stages of GFR/CKD

  • Stage 1 CKD. Creatinine = 60-120 mcmol/L, i.e. kidney damage with normal kidney function.
  • Stage 2. Creatinine = 60-120
  • Stage 3A. Creatinine = 120-150
  • Stage 3B. Creatinine 150-200
  • Stage 4. Creatinine >200
  • Stage 5. Creatinine > 400.

Note 1. The values are approximate, e.g. someone may have a creatinine of 151 and be in Stage 3A
Note 2. But, the big but. These number ranges (and what we have said is a ‘normal’ creatinine/GFR’) are so neat, they are clearly made up (wrong) – as are all the CKD stages. But it is the simple table that doctors and nurses use to guide investigation and treatment.

Summary

We have described what is a high blood creatinine level – i.e. a blood creatinine > 200 mcmol/L. This is high and always a problem. We hope this has been helpful.

Other resources

Here is more information on the problems with creatinine/GFR on our sister CKD Explained website.

What is a normal creatinine level?
What is a normal GFR?